Treatments for Osteo and Rheumatoid Arthritis

As we get older, many of us begin to notice the snap, crackle, and pop of some of our most-used joints as we try to go about our day bending and twisting, just like we did in our youth. We might go throughout our day in extreme discomfort asking ourselves, “Whatever happened to my rubber-band-like tendons?” The reality is that wear and tear, disease, and genetics have a lot to do with the pain involved in each step and bend throughout our day and it doesn’t seem to get any better as time goes by. So, as cartilage decays or gets inflamed, the question asked now is, “what kind of drug, supplement, or procedure is available to stop the pain?” Let’s attempt to answer these questions as we explore treatments for different types of arthritis.

What is Osteoarthritis?

The word “arthritis” literally means arthron (joint) and -itis (inflammation) and is defined as painful inflammation and stiffness of the joints. Osteoarthritis, the most common form of arthritis, usually affects the large and small “arthrons” of our bodies (knees, wrists, ankles, etc.). The most common reason individuals develop osteoarthritis is due to progressive wear and tear of a given joint, although a major trauma to the area can also cause an osteoarthritic state. Osteoarthritis starts in the connective tissue region of the joint and eventually begins to bridge the two opposing bones to graft or fuse into each other. This phenomenon causes for a very uncomfortable and often painful condition. Some of the most common causes of this type of arthritis are obesity, immobility, and prior joint trauma¹, just to name a few.

What is Rheumatoid Arthritis?

Rheumatoid arthritis (or RA) is denoted as an autoimmune disorder in which the immune cells of our bodies attack our own tissues, in this case our connective tissues or joints. The result of this attack is inflamed joints followed by stiffness and pain. Although this disease can and will act upon other parts of the body involving larger joints, the typical areas of attack are the wrists and hands. These symptoms can develop either quickly or gradually over long periods of time. The result of rheumatoid arthritis doesn’t only involve typical arthron, but can lead to inflammation of the lungs and heart as well as decreased erythrocyte count^2-4. To date, approximately 1.3 million people in the United States suffer from RA⁵.

How Do You Treat Arthritis?

Although there is no known cure for osteo or rheumatoid arthritis, there are many treatments. Joint replacement surgery, medication, diet and exercise, nutritional supplements, etc. are all viable options. Physical therapy in some cases has been shown to decrease pain and delay the need for surgery⁶. Prescription medications such as Methotrexate, Anakinra, and anti-TNF drugs have been shown to assist in reducing inflammation by cutting it off at the source⁷. Conversely, non-prescription (ie, OTC) medications such as acetaminophen and ibuprofen are very successful in reducing pain and inflammation by acting as antinociceptive and non-steroidal anti-inflammatory drugs⁸. Holistic medicine has also risen to the challenge with new discoveries of fascinating molecules found in plants and even animals. For example, Hyaluronic acid is used as a treatment for osteoarthritis, creating an analgesic effect as well as rebuilding and cushioning knee cartilage⁹. Methylsulfonylmethane (MSM) is an organic, sulfur-containing compound found in certain foods and is known to have some pretty amazing anti-inflammatory properties¹⁰. And then, of course, the ever so popular amino sugar, glucosamine. It is one of the most abundant monosaccharides in our bodies and actually does wonders for repairing and reducing the inflammation of some of our most-used joints^11,12. So, whether one chooses holistic medicine, prescription drugs or physical therapy, arthritis can be treated.

Conclusion

It is inevitable that, over time, whether genetically or environmentally influenced, connective tissue degradation does in fact occur. This degradation can occur quickly or develop over time. Although there is no magic pill or therapeutic exercise that will give us back the flexible joints of a teenager, science and technology have caught up with the times to offer us helpful and viable solutions on how to keep our most-used joints healthy and happy.

Author: Chad Brey, a California State University, Northridge alumnus, has since worked as a chemist for various analytical and research facilities such as Amgen, Baxter, and Nusil Technology. Since 1997 he has worked in the dietary supplement industry for companies such as Earthwise Nutrition (formerly known as Great Earth Vitamins) and has earned a number of certificates as an IACET-certified dietary supplement specialist. Chad has written dozens of technical articles on the specifics of how certain dietary supplements work. Chad has formulated and developed small and large molecules in research and development laboratories since 2003 and continues to consult others in R&D today.

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